Skip to main content
. 2021 Nov 24;47(1):21. doi: 10.3892/or.2021.8232

Figure 4.

Figure 4.

Inhibition of miR-577 facilitates pancreatic cancer cell proliferation, migration and invasion. (A) RT-qPCR was utilized to detect miR-577 expression in the pancreatic cancer tissue and adjacent tissue samples (n=37). (B) RT-qPCR was employed to detect miR-577 expression in pancreatic cancer cell lines (SW1990, PANC-1, CAPAN-1 and BXPC-3) and normal pancreatic ductal epithelial cells (HPDE6-C7). (C) SW1990 cells were transfected with miR-con inhibitors or miR-577 inhibitors to construct the knockdown expression model of miR-577, and the transfection efficiency was detected by RT-qPCR. (D) An MTT assay was employed to detect the effect of miR-577 inhibition on SW1990 cell proliferation. (E) Transwell assays were utilized to detect the effects of miR-577 inhibition on SW1990 cell migration and invasion. Scale bar, 50 µm. All of the experiments were performed in triplicate. **P<0.01 and ***P<0.001. miR, microRNA RT-qPCR, reverse transcription-quantitative PCR.