Table 1.
Organism | Tissue | Cell Type or Sample Source | Basal Expression | Reference |
---|---|---|---|---|
Human | Periphery | CD14++CD16- monocyte | + | (7, 72)AB,A |
CD14+CD16+ monocyte | + | (7, 72)AB,A | ||
B cell | + | (6)A | ||
NK cell | ++ | (6, 73)A,B | ||
αβ T cell | -/+ | (6)A | ||
γδ T cell | + | (6)A | ||
Eosinophil | + | (67)A | ||
Basophils | ++ | (67)A | ||
Neutrophil | + | (7, 67, 73, 74)A,A,A,B | ||
In vitro cultured | Myeloid derived dendritic cell | + | (7)B | |
Myeloid derived monocyte | + | (7)B | ||
6-sulfo LacNAc+ dendritic cell | ++ | (73)B | ||
Spleen | Splenic red pulp macrophage | ++++ | (5)C | |
Splenic red pulp granulocyte | ++++ | (5)C | ||
Synovial Joints | Synovial macrophage | ++ | (71)C | |
Liver | Kupffer cell | – | (5)C | |
Mouse | Periphery | Peripheral leukocyte | -/+ | (38, 39, 75)A,A,B |
Neutrophil | + | (76)A | ||
Monocyte | + | (76)A | ||
Spleen | Splenic red pulp macrophage | ++++ | (38, 77)BC,D | |
Peritoneum | Peritoneal macrophage | -/+ | (38, 78)A,B | |
Bone Marrow | Macrophage | ++ | (38)BC | |
Thymus | Macrophage | ++ | (38)BC | |
Liver | Kupffer cell | – | (38)B | |
Lungs | Lung homogenate | -/+ | (77)D | |
Rat | Periphery | Peripheral leukocyte | -/+ | (79)A |
Neutrophil | -/+ | (79)AB | ||
Monocyte | -/+ | (79)AB | ||
Lungs | Lung homogenate | + | (80)E | |
Spleen | Splenic red pulp macrophage | ++++ | (79)AE | |
Canine | Periphery | Peripheral leukocyte | -/+ | (4)A |
CD8+ T cell | + | (4)A | ||
Spleen | Splenic red pulp macrophage | ++++ | (4)AC | |
Liver | Kupffer cell | – | (4)AC |
Expression is represented on a scale of – (not detected) to ++++ (highly expressed). A limitation encountered when comparing CD11d expression across studies was the variation in detection method: flow cytometry (A), immunocytochemistry (B), immunohistochemistry (C), quantitative PCR (D), and western blot (E).