Table 1.

Differences and similarities between IgAV with nephritis and IgAN(48, 49).

Characteristics	IgA Vasculitis with nephritis	IgA Nephropathy
Onset	Children younger than 10 years of age	More common in adulthood
Organs involved	Systemic or single-organ limited (skin, kidney, joint, gastrointestinal tract, etc. )	Kidney
Disease course	Acute, with spontaneous resolution	Chronic and progressive
Gender preference	More common in male (about 2:1)
Abnormal IgA	Galactose-deficient IgA1
Light microscopy	Mesangial proliferation, endocapillary hypercellularity, segmental sclerosis, crescents
Immunofluorescence microscopy	IgA1 dominant deposits in the glomerular mesangium
Outcome	More severe in adults