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. 2021 Nov 8;9:766107. doi: 10.3389/fchem.2021.766107

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Copyright © 2021 Suzuki, Ichinohe, Sugawara, Kida, Murase, Zhang, Yamada, Hattori, Oshima and Kikuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plausible synthetic pathways for the production of pentacyclic compound 1 and its derivatives using the diversity-enhanced extracts of C. officinalis.