Figure 1.

Vitamin A supplements at the time of parainfluenza virus infections reduce lung lesions scored 5-6 weeks post-infection. Data are from one of three experiments demonstrating the reduction of lung lesions in CF mice supplemented with vitamin A at the time of a virus infection. Lesions were given relative scores. Each symbol represents a different test mouse (no lesions were observed in control, uninfected mice). In each of the three experiments, the vitamin A-supplemented mice (CF+VitA) exhibited significantly or marginally reduced scores for interstitial inflammation, alveolar inflammation, and septal thickening at weeks 5-6 post-virus infection compared to mice that received no supplement (CF). Means with standard deviations are shown. Mann Whitney tests were performed to compare groups (*p < .05, **p < .01).