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. 2021 Nov 9;12:770822. doi: 10.3389/fimmu.2021.770822

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Copyright © 2021 Chen, Wang, Guo, Xie, Evivie, Song, Li and Huo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A). The bactericidal effect of CFS on Escherichia coli ATCC25922 was quantified by the lgCFU value of the number of viable bacteria. The control group was treated with saline, and the MRS medium without bacteria was adjusted to pH = 4. (B) The contact dependence inhibition effect was expressed by the number of viable bacteria under the co-cultivation of Escherichia coli ATCC25922 and L. plantarum KLDS 1.0344, and the control group is Escherichia coli ATCC25922 cultured alone. (C) Lactic acid content in the cell-free fermentation supernatant at different fermentation times. (D) Linear analysis of lactic acid content and bacteriostatic circle diameter. The values obtained for all tests are the mean ± SD (n = 3 independent experiments).