Figure 3.

(A) Hyperpigmented plaque in the interscapular region, suggestive of cutaneous lichen amyloidosis. (B) Contrast-enhanced computed tomography (CECT) (axial section) of abdomen showing a cystic mass lesion (16 × 12 × 12 cm) with peripheral enhancement in the right suprarenal region (blue arrow). (C) CECT (axial section) of abdomen showing a hypodense lesion with peripherally enhancing solid component in segment VIII of the liver (white arrow). (D) Low-power photomicrograph of liver biopsy showing liver parenchyma (right side) being infiltrated by a cellular tumor (left side) (×40, hematoxylin & eosin (H and E)). (E) High-power microphotograph to show sheets of tumor cells with eccentrically placed nuclei, and abundant granular eosinophilic cytoplasm are seen, consistent with pheochromocytoma. Brisk and atypical mitoses (black arrow) are seen (×400, H and E). (F) Tumor cells showing positive staining for chromogranin immunohistochemistry (IHC), suggesting neuroendocrine tumor (×100, DAB). Tumor cells with negative IHC for carcinoembryonic antigen (G) (×200, DAB) and calcitonin (H) (×400, DAB) ruling out medullary thyroid carcinoma.