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. Author manuscript; available in PMC: 2021 Nov 30.
Published in final edited form as: Dig Dis Sci. 2019 Oct 30;65(6):1761–1766. doi: 10.1007/s10620-019-05900-3

Table 2:

Univariate Risk Factors for Recurrence of CDI

CDI Recurrence

YES N= 22 NO N=53 P value
Mean Age (±SD) 57.1 ± 18.0 58.5 ± 14.4 0.730

Female (N,%) 15 (68.2%) 37 (69.8%) 0.889

Race (N,%) 0.249
 Black 1 (4.5%) 10 (18.9%)
 White 18 (81.8%) 38 (71.7%)

Mean BMI (±SD) 28.5 ± 6.6 28.4 ± 6.6 0.969

Received Antibiotics prior to Diagnosis (N,%) 15 (68.2%) 41 (77.4%) 0.405

Antibiotic Type 0.076
Beta- Lactam 8 (36%) 10 (18.8%)
Fluoroquinolone 1 (4.5%) 14 (26.4%)
Lincosamide 3 (13.6%) 2 (3.7%)
Macrolide 0 2 (3.7%)
Metronidazole 2 (9%) 1 (1.8%)
Nitrofurantoin 0 1 (1.8%)
Peptide Antibiotic 0 5 (9.4%)
Rifamycin 0 1 (1.8%)
Sulfa Drug 1 (4.5%) 2 (3.7%)
None 7 (32%) 15 (28.3%)

Prior PPI use (N, %) 10 (45.5%) 31 (58.5%) 0.301

History of Cirrhosis (N,%) 2 (9.1%) 3 (5.7%) 0.626

Dietary restrictionsN,% 0.248
 No 19 (86.4%) 49 (92.5%)
 Vegan 1 (4.5%) 0 (0.0%)
 Vegetarian 2 (9.1%) 1 (1.9%)
 Gluten Free 0 (0.0%) 1 (1.9%)
 Lactose Free 0 (0.0%) 2 (3.8%)

Smoking status (N,%) 0.220
 Never 15 (68.2%) 24 (46.2%)
 Former 6 (27.3%) 25 (48.1%)
 Current 1 (4.5%) 3 (5.8%)

Diagnosis of Irritable Bowel Syndrome (N,%) 0 (0.0%) 8 (16.3%) 0.051

Baseline diarrhea or constipation (N,%) 0.575
 No 18 (81.8%) 36 (70.6%)
 Diarrhea 1 (4.5%) 7 (13.7%)
 Constipation 2 (9.1%) 7 (13.7%)
 Both 1 (4.5%) 1 (2.0%)

Baseline Bristol Score (±SD) 2.7 ± 1.2 3.3 ± 1.2 0.084

Ursodiol Use (N,%) 0 (0.0%) 0 (0.0%) 0.0

Cholestyramine Use (N,%) 2 (9.1%) 0 (0.0%) 0.085

Colestipol Use (N,%) 0 (0.0%) 1 (1.9%) 1.0

CDI Treatment Regimen (N,%) 0.030
 Metronidazole 9 (40.9%) 8 (15.1%)
 Vancomycin 13(59.1%) 45 (84.9%)

Test Used for Diagnosis (N,%) 0.007
 PCR 5 (22.7%) 30 (56.6%)
 EIA Toxin 17 (77.3%) 23 (43.4%)

Mean White Blood Cell Count (±SD) 8.2 ± 3.3 14.8 ± 18 0.147

Mean Platelet Count (±SD) 206.3 ± 72. 270.9 ± 114.8 0.030