. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: J Mol Cell Cardiol. 2021 Jun 1;158:115–127. doi: 10.1016/j.yjmcc.2021.05.016

Table 1.

Echocardiographic parameters in mTORC1^iSA and Control mice at 28 weeks.

Parameter	Control (n=8)	mTORC1^iSA (n=9)

LVAWd (mm)	0.99 ± 0.06	1.12 ± 0.05
LVAWs (mm)	1.44 ± 0.08	1.63 ± 0.06
LVIDd (mm)	3.97 ± 0.07	3.61 ± 0.09^**
LVIDs (mm)	2.81 ± 0.05	2.31 ± 0.07^**
LVPWd (mm)	0.96 ± 0.06	1.01 ± 0.08
LVPWs (mm)	1.35 ± 0.05	1.42 ± 0.10
EF (%)	56.01 ± 2.07	66.38 ± 1.80^**
FS (%)	28.92 ± 1.37	36.04 ± 1.39^**
Heart rate (bpm)	433.9 ± 16.48	384.8 ± 7.35^*
Relative Wall Thickness	0.49 ± 0.02	0.59 ± 0.03^*
E/A	1.46 ± 0.11	1.83 ± 0.13
E/e’	33.94 ± 3.30	28.23 ± 3.24
IVRT/RR	0.15 ± 0.01	0.15 ± 0.01

LVAWd: Left Ventricular Anterior Wall in diastole. LVAWs: Left Ventricular Anterior Wall in systole. LVIDd: Left Ventricular Internal Diameter in diastole. LVIDs: Left Ventricular Internal Diameter in systole. LVPWd: Left Ventricular Posterior Wall in diastole. LVPWs: Left Ventricular Posterior Wall in systole. EF: Ejection Fraction. FS: Fractional Shortening. Statistical significance was calculated using unpaired two-tailed Student’s t test;

p<0.05

^**

p<0.01.