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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: AIDS. 2021 Apr 1;35(5):717–726. doi: 10.1097/QAD.0000000000002824

Table 4:

Relationship between placenta pathology and preterm delivery, size for gestational age and low birthweight.

1Preterm delivery 1Size for gestational age (<10th centile) 1Low birthweight (<2500g)

Y (%) N (%) P Y (%) N (%) P Y (%) N (%) P
Percentile placental weight 0. 7 0. 1 1. 0
 <10th 2 (23) 41 (34) 7 (58) 36 (30) 4 (36) 39 (33)
 >10th 6 (67) 80 (66) 5 (42) 81 (69) 7 (64) 79 (66)
Missing 1 (11) 0 (0) 0(0) 1(1) 0 (0) 1(1)

Cord insertion 0. 2 1.0 0. 1
 Central 3 (33) 17 (14) 2 (17) 18 (15) 4 (36) 16 (13)
 Off centre 5 (56) 83 (69) 8 (67) 80 (68) 7 (64) 81 (68)
 Marginal 0 (0) 16 (13) 1 (8) 15 (13) 0 (0) 16 (14)
Missing 1 (11) 5 (4) 1 (8) 5 (4) 0 ( 0) 6 (5)

Meconium exposure 1. 0 0.01 0. 7
+ 1 (11) 24 (19) 6 (50) 19 (16) 1 (9) 24 (20)
8 (89) 97 (80) 6 (50) 99 (84) 10 (91) 95 (78)

Chorioamnionitis
Maternal Inflammatory Response 0. 4 0. 4 0. 4
+ 0 (0) 19 (16) 3 (25) 16 (14) 0 19 (16)
9 (1 00) 102 (84) 9 (75) 102 (86) 11 (100) 100 (84)
Fetal Inflammatory Response 0. 4 1. 0 0. 2
+ 0 20 17) 2 (17) 18 (15) 0 20 (17)
9 (1 00) 101 (83) 10 ( 83) 100 (85) 11 (100) 99 (83)

Chronic Deciduitis 1. 0 0.4 0. 4
+ 1 (11) 13 (11) 0 14 (12) 2 (18) 12 (10)
8 (89) 108 (89) 12 (100) 104 (88) 9 (82) 107 (90)

Decidual arteriopathy 0.07 0. 5 0. 1
+ 2 (22) 5 (4) 1 (8) 6 (5) 2 (18) 5 (4)
7 (78) 116 (96) 11 ( 92) 112 (95) 9 (82) 114 (96)

Maternal Vascular Malperfusion (MVM) 0.002 0.09 <0.0001
+ 7 (78) 29 (24) 6 (50) 30 (25) 10 (91) 26 (22)
2 (23) 92 (76) 6 (50) 88 (75) 1 (9) 93 (78)
1

To assess potential risk factors for preterm delivery (<37 weeks gestational age), size for gestational age (<10th percentile) and low birth weight (<2500g), we compared differences between groups using the chi2 test or Fisher’s exact test.