Table 2:

U.S. Population Costs

	Total Annual Costs (billions)			Differences (billions)
	Aflibercept	Laser	Observation	A-L	O-L	A-O
2020	$2.03 billion	$0.80 billion	$0.91 billion	$1.24 billion	$0.11 billion	$1.12 billion
2021	$2.10 billion	$0.92 billion	$1.03 billion	$1.18 billion	$0.11 billion	$1.07 billion
2022	$2.25 billion	$1.05 billion	$1.16 billion	$1.20 billion	$0.11 billion	$1.09 billion
2023	$2.44 billion	$1.20 billion	$1.31 billion	$1.24 billion	$0.11 billion	$1.13 billion
2024	$2.62 billion	$1.35 billion	$1.46 billion	$1.27 billion	$0.11 billion	$1.16 billion
2025	$2.80 billion	$1.50 billion	$1.61 billion	$1.31 billion	$0.12 billion	$1.19 billion
2026	$2.99 billion	$1.65 billion	$1.77 billion	$1.34 billion	$0.12 billion	$1.22 billion
2027	$3.17 billion	$1.80 billion	$1.92 billion	$1.37 billion	$0.12 billion	$1.25 billion
2028	$3.35 billion	$1.95 billion	$2.08 billion	$1.40 billion	$0.13 billion	$1.28 billion
2029	$3.54 billion	$2.10 billion	$2.23 billion	$1.44 billion	$0.13 billion	$1.31 billion
Cumulative Undiscounted*	$27.29 billion	$14.30 billion	$15.48 billion	$12.99 billion	$1.17 billion	$11.82 billion
Cumulative Discounted**	$23.61 billion	$12.25 billion	$13.28 billion	$11.35 billion	$1.03 billion	$10.33 billion

A: Aflibercept; L: Laser; O: Observation

^*Sum of the costs from 2020 through2029.

^**Discounts cost from 2021 through 2029 by 3% for each year in the future and then sums them together.