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. 2021 Nov 30;29(6):8109–8125. doi: 10.1007/s11356-021-17824-5

Fig. 8.

Fig. 8

Aviptadil protects type 2 pneumocytes by binding to VPAC-1 receptor and preventing the action of caspase induced by the coronavirus which also binds to the type II pneumocytes with the help of ACE-II receptor. Caspase instructs the cells to kill themselves promoting apoptosis