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Map of the β-globin locus on human chromosome 11. The PYR complex binds to a 250-bp pyrimidine-rich sequence (rectangle Y · R) located between the fetal (γ) and adult (δ and β) β-globin-like genes. β-Globin locus control region (LCR) DNase I-hypersensitive sites 1 through 4 are indicated by downward arrows.
