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. 2021 Nov 23;17:739–769. doi: 10.2147/VHRM.S328096

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© 2021 Zuraini et al.

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Bioactive compounds and protective effects of orange (Citrus sinensis) in on the monoamine oxidase (MAO) activity, phosphodiesterase (PDE) activity, and angiotensin-converting enzyme (ACE) activity in the heart. Orange extract/juice contains compounds that helps in modulation of the renin-angiotensin-aldosterone system (RAAS) thus helps in lowering the diastolic and systolic blood pressure.