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. 2021 Nov 10;11:747094. doi: 10.3389/fcimb.2021.747094

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Copyright © 2021 Dai, Zhao, Li, Li, You, Zhu and Liao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gene expression analysis enriched in the “Cytokine–cytokine receptor interaction” pathway of CD4⁺CD8^low+, CD8^medium+, CD8^high+, CD8^high αα^+,and CD8^high αβ⁺ T cell populations. (A) Heat map of selected immune genes enriched in the “Cytokine–cytokine receptor interaction” pathway. (B) Gene interaction network analysis based on WGCNA analysis and STRING database. The gray line indicates the potential interaction relationship based on the WGCNA analysis. The green line indicates the potential interaction relationship based on the STRING database. The pink line indicates the potential interaction based on both the WGCNA analysis and STRING database. Red nodes represent hub genes.