Table 2.
Iron regulators in cancer prognosis.
| Altered Player | Cancer | Regulation | prognosis | Ref. |
|---|---|---|---|---|
| TFR1 | hepatic carcinoma | up | poor | (176,177) |
| TFR1 | ovarian cancer | up | poor | (29) |
| TFR1 | lung cancer | up | poor | (178) |
| TFR1 | gastric cancer | up | poor | (179) |
| TFR1 | glioblastoma | up | poor | (180) |
| TFR2 | glioblastoma | up | good | (181) |
| TFR1 | colorectal cancer | up | good | (182) |
| FPN1 | breast cancer | down | poor | (45) |
| FPN1 | lung cancer | down | poor | (178) |
| FPN1 | adrenocortical carcinoma | down | poor | (183) |
| FPN1 | multiple myeloma | down | poor | (43) |
| FPN1 | clear cell renal cell carcinoma | down | poor | (184) |
| STEAP3 | glioblastoma | up | poor | (39) |
| STEAP1 | breast cancer | up | good | (185) |
| STEAP2 | breast cancer | up | good | (185) |
| STEAP4 | breast cancer | up | good | (185) |
| Hepcidin | breast cancer | up | poor | (186) |
| FTL | ovarian cancer | up | poor | (187) |
| DMT1 | ovarian cancer | up | poor | (187) |
| HAMP | ovarian cancer | up | poor | (187) |
| DMT1 | hepatocellular carcinoma | low | poor | (65) |