Table 3.
Iron in Cancer Therapy.
| Name | Mechanism | Ref. |
|---|---|---|
| Cyst(e)inase | degrading cysteine | (133,192,193) |
| DFO | iron depletion | (194) |
| DFO | iron depletion | (195) |
| Triapine | iron depletion | (196) |
| Dp44mT | iron depletion | |
| Fusaricide | iron depletion | (62) |
| Ga | iron depletion | (197) |
| Tris (8-quinolinolato) Gallium (III) (KP46) | iron depletion | (198) |
| Gallium Mallotate | iron depletion | (198) |
| Ferrocene derivatives | elevated iron levels | (199) |
| Ferumoxytol | elevated iron levels | (200) |
| ascorbic acid | ferroptosis | (201–205) |
| salinomycin derivatives | ferroptosis inducers | (206) |
| DMT1 inhibitor | target DMT1 | (68) |
| HFn-PTX | target TFR1 | (207) |
| DOX-FTH | target TFR1 | (179,208) |
| miR-375 | target SLC7A11 | (209) |
| miR-148a | targeting TFR1 | (32) |
| miR-184 | targeting HAMP | (210) |
| miR-200b | targeting ferritin | (211) |