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. 2021 Nov 24:NEJMc2108120. doi: 10.1056/NEJMc2108120

Table 1. Severity of SARS-CoV-2 Reinfections as Compared with Primary Infections in the Population of Qatar.

Disease Outcome* Reinfection Primary Infection Odds Ratio (95% CI)
no. of persons with outcome/no. of persons with infection that was not severe, critical, or fatal
Severe disease 4/1300 158/6095 0.12 (0.03–0.31)
Critical disease 0/1300 28/6095 0.00 (0.00–0.64)
Fatal disease 0/1300 7/6095 0.00 (0.00–2.57)
Severe, critical, or fatal disease 4/1300 193/6095 0.10 (0.03–0.25)
*

Severe disease, critical disease, and fatal disease were defined on the basis of the World Health Organization criteria for classifying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection severity and coronavirus disease 2019 (Covid-19)–related death.

Reinfections were matched with up to five primary infections according to sex, 5-year age group, nationality, and calendar week of polymerase-chain-reaction testing. The final sample therefore includes persons with reinfection who were matched to five or fewer persons with primary infection.