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. 2021 Nov 10;12:772928. doi: 10.3389/fphar.2021.772928

TABLE 6.

Daily intake value (µg/day) of the analyzed herbal medicines measured here (taking recommended dosage according Table 4) compared to recommended values by United States Pharmacopeia (USP).

Elements Daily intake for this study (µg/day) (taking recommended dosage according Table 4) Permitted daily exposure for elemental impurities (Oral PDE) (µg/day)
Pasalix® Calman® Serenus® Prakalmar® Calmasyn® Maracugina®
As 2.81 5.14 1.78 1.88 9.72 2.54 15
Ba 2.59 0.510 < LOD 0.190 2.08 6.60 1,400
Cd 0.021 < LOD 0.068 0.00900 0.43 0.12 5
Co 1.32 2.85 1.26 0.621 5.48 1.37 50
Cr 0.820 0.120 0.830 0.620 2.64 1.15 11,000
Cu 3.24 3.32 0.830 4.55 24.9 2.54 3,000
Fe 35.4 38.3 1,640 40.8 106 208
Pb 3.03 4.39 2.05 1.66 10.4 2.88 5

< LOD - analyte concentrations were below the limits of detection.