Table 2.

Clinical and laboratory data at the last follow up visit.

Patient N	Age (y)/years of f/u	Treatment	Ca blood (mg/dl)	P blood (mg/dl)	PTH (pg/ml) (14–53)	1,25-D (pmol/l) (39–160)	Ca/Creatinine urine (mg/mg)	US	eGFR (mL/min/ 1.73 m2)
1	5/4.6	Diet-Low sodium Low calcium Low vitamin D	10.1 (N 8.8–10.8)	5.8 (N 3.2–5.8)	5.5	130	0.6 (N < 0.4)	NC (grade 3)	120
2	2/1.1	No	9.1 (N 8.8–10.8)	4.4 (N 4–6.5)	17	210	N/a	N/a	159
3	8/7.1	TZD 12.5 mg/day Citrate Diet-Low sodium	9.6 (N 8.8–10.8)	5 (N 3.2–5.8)	13.6	191	0.28 (N < 0.2)	NL → stone excretion → N	140
4	17/6	TZD 25 mg/day Phosphor supplement Citrate	9.8 (N 8.4–10.2)	3.7 (N 2.5–5)	11.7	370	0.15 (N < 0.2)	N	159
5	2/1.9	No	10.1 (N 8.8–10.8)	5.2 (N 4–6.5)	18.8	170	0.5 (N < 0.4)	N	117
6	17/14	TZD 25 mg/day Citrate Diet- Low sodium	10.6 (N 8.4–10.2)	5.8 (N 2.5–5)	7	233	0.4 (N < 0.2)	NL	84
7	12/5	TZD 12.5 mg/day Citrate Diet- Low sodium	10.8 (N 8.4–10.2)	4.9 (N 3.2–5.8)	6	196	0.25 (N < 0.2)	NL	130
8	3/2.9	No	10.9 (N 8.8–10.8)	4.6 (N 3.2–5.8)	10.9	168	0.2 (N < 0.4)	N	161
9	2/1.4	Diet-Low sodium	10.3 (N 8.8–10.8)	4.4 (N 4–6.5)	14	262	0.6 (N < 0.4)	NC (grade 3)	192
10	4/2	TZD 6.25 mg/day Diet-Low sodium	11.2 (N 8.8–10.8)	4.9 (N 3.2–5.8)	14	158	0.46 (N < 0.4)	NC (grade 3)	88
Summary data	follow up (median) 3.75 (range 1.1–14 y)		Mean ± SD 10.3 ± 0.6	Mean ± SD 4.87 ± 0.6	Mean ± SD 12 ± 4.5	Mean ± SD 209 ± 65	Hypercalciuria-7	NC-3 NL-2 N-4	CKD-2

eGFR, estimated glomerular filtration rate using modified Schwartz Formula (14); Y, years; n/a, not available; NC, nephrocalcinosis; NL, nephrolithiasis; N, normal; TZD, Disothiazide; Ca, calcium; PTH, parathyroid hormone; US, ultrasound.

Normal blood calcium values for age are noted in parenthesis.

Normal urinary calcium/creatinine ratios for age are noted in parenthesis (13, 14).