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. 2021 Oct 31;13(10):e19167. doi: 10.7759/cureus.19167

Table 1. Summary of previously reported cases of superficial tumors treated with radiotherapy using a hydrogen peroxide bolus.

fr., fraction; EQD2α/β10, the equivalent dose in 2 Gy per fraction with α/β of 10; M, months; Refs, references; NA, not assessed; PR, partial response; CR, complete response. Adverse effect was assessed by the Common Terminology Criteria for Adverse Events 4.0, where G indicates grade. *Japanese book (ISBN: 978-4-86705-804-6).

Cancer type n Radiation Dose/fr. EQD2α/β10  Follow-up (M) Outcome Adverse effect Refs
Breast cancer 1 Electrons 48 Gy/12 fr. 56 Gy 3 PR Dermatitis (G1) [6]
Melanoma 1 Electrons 48 Gy/12 fr. 56 Gy 12 CR Dermatitis (G1) [6]
Malignant fibrous histiocytoma 1 Electrons 48 Gy/12 fr. 56 Gy 3 PR Dermatitis (G1) [6]
Skin squamous cell carcinoma 1 Electrons 48 Gy/12 fr. 56 Gy 1 PR Dermatitis (G1) [6]
Extramammary Paget's disease 1 Electrons 48 Gy/12 fr. 56 Gy 12 CR Dermatitis (G1) [6]
Angiosarcoma 2 Electrons 52.5 Gy/21 fr. 54.7 Gy NA NA Dermatitis (G2, 50%) *
Malignant trichilemmoma 1 X-rays 54 Gy/27 fr. 54 Gy 3 CR NA *
Penile cancer 1 X-rays 64 Gy/32 fr. 64 Gy NA CR Dermatitis (G3) *
Breast cancer 1 X-rays 51 Gy/17 fr. 55.2 Gy 4 CR Dermatitis (G1) Present case