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. 2021 Nov 10;12:697298. doi: 10.3389/fimmu.2021.697298

Table 5.

Toxicities recorded in both ICI and ICI+BTT treatments.

Toxicity Grade Total No. (%)
1No. (%) 2No. (%) 3No. (%)
Arthralgia 1 (2.2) 0 (0.0) 1 (2.2) 2 (4.3)
Asthenia 2 (4.3) 0 (0.0) 1 (2.2) 3 (6.5)
Dermatitis 0 (0.0) 0 (0.0) 1 (2.2) 1 (2.2)
Diarrhea 2 (4.3) 1 (2.2) 0 (0.0) 3 (6.5)
Dypnea 0 (0.0) 1 (2.2) 0 (0.0) 1 (2.2)
Infection 0 (0.0) 1 (2.2) 0 (0.0) 1 (2.2)
Creatinine increase 5 (10.9) 1 (2.2) 0 (0.0) 6 (13.0)
Hyperamylasemia 1 (2.2) 0 (0.0) 1 (2.2) 2 (4.3)
Hypertransaminasemia 2 (4.3) 0 (0.0) 1 (2.2) 3 (6.5)
Hypophosphatemia 0 (0.0) 1 (2.2) 0 (0.0) 1 (2.2)
Hypothyroidism 1 (2.2) 0 (0.0) 0 (0.0) 1 (2.2)
Neuropathy 0 (0.0) 1 (2.2) 0 (0.0) 1 (2.2)
Neutropenia 0 (0.0) 1 (2.2) 0 (0.0) 1 (2.2)
Pneumonitis 0 (0.0) 2 (4.3) 0 (0.0) 2 (4.3)
Skin rash 1 (2.2) 1 (2.2) 0 (0.0) 2 (4.3)
Lipase increase 1 (2.2) 0 (0.0) 1 (2.2) 2 (4.3)
Sepsis 0 (0.0) 0 (0.0) 1 (2.2) 1 (2.2)
Skin toxicity 0 (0.0) 0 (0.0) 1 (2.2) 1 (2.2)