TABLE 3.

Association between EEG predictor variables and cognitive score changes from baseline to post-operative day 1.

	Cognitive outcome variable: Change in attention score
EEG predictor variable	Correlation		Unadjusted proportional odds models		Adjusted proportional odds models*
	Spearman ρ (95% CI)	p-value	Odds ratio (95% CI)	p-value	Odds ratio (95% CI)	p-value
Pre-operative AUC	0.10 (−0.18, 0.37)	0.49
Intra-operative AUC	−0.05 (−0.32, 0.23)	0.73
Difference in AUC	−0.12 (−0.39, 0.16)	0.39
Crossover location (N = 42**)	0.29 (−0.02, 0.55)	0.060	1.25 (0.99, 1.58)	0.058	1.25 (0.99, 1.59)	0.066
	Cognitive outcome variable: Change in delirium severity score
EEG predictor variable	Correlation		Unadjusted linear regression models		Adjusted linear regression models*
	Spearman ρ (95% CI)	p-value	Mean difference (95% CI)	p-value	Mean difference (95% CI)	p-value
Pre-operative AUC	−0.08 (−0.35, 0.22)	0.61
Intra-operative AUC	0.06 (−0.23, 0.34)	0.67
Difference in AUC	0.17 (−0.12, 0.44)	0.24
Crossover point (N = 42**)	−0.31 (−0.57, 0.01)	0.054	−0.10 (−0.23, 0.03)	0.11	−0.10 (−0.23, 0.03)	0.12

*Adjusted proportional odds model included the following covariables: age, body mass index, cardiovascular disease.

**Restricted analysis excludes eight participants with atypical MSE curves (multiple crossover points).

Values that are significant or nearly significant are bolded.