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. 2021 Dec 1;131(23):e150506. doi: 10.1172/JCI150506

Figure 4. Location of mutated residues in HN that arose during long-term infection.

Figure 4

(A) Overview of HN (PDBID:4MZA) and F (PDBID:6MJZ) on the viral surface. Residues that showed variant changes of greater than 25% in the HN protein during long-term infection for (B) patient 1 and (C) patient 2 are labeled. The backbone is colored in green, and the side chains are labeled by standard atom coloring. Residues are labeled with the original reference amino acid and not the changes observed. Note the localization of minor variants to 2 of the known active sites of HPIV3 HN protein.