WT mice underwent CLP or sham surgery and (A) peritoneal lavage at 22 hours and (B) peripheral blood at 0, 4, 9, and 22 hours were analyzed for MIF and MIF-2 by ELISA. (A) n = 4 to 10 animals, 1-way ANOVA with Tukey’s multiple-comparison test. (B) n = 6 to 22 animals, 2-way ANOVA with Bonferroni’s multiple-comparison test. *P < 0.05; **P < 0.01; ****P < 0.0001.