Figure 1. MIF and MIF-2 levels increase in sepsis.
WT mice underwent CLP or sham surgery and (A) peritoneal lavage at 22 hours and (B) peripheral blood at 0, 4, 9, and 22 hours were analyzed for MIF and MIF-2 by ELISA. (A) n = 4 to 10 animals, 1-way ANOVA with Tukey’s multiple-comparison test. (B) n = 6 to 22 animals, 2-way ANOVA with Bonferroni’s multiple-comparison test. *P < 0.05; **P < 0.01; ****P < 0.0001.