Figure 1.
(A) Structure of proglucagon, post-translational processing and the major targets of constituent bioactive peptides: glucagon, GLP-1, GLP-2, oxyntomodulin, glicentin and glicentin-related pancreatic polypeptide. (B) Numbers of peer-reviewed publications on proglucagon-derived peptides showing particularly strong surge of research on GLP-1. (C) Publication count by geographical location divided by population of each country (source: PubMed).