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. 2021 Nov 11;8:766996. doi: 10.3389/fcvm.2021.766996

Table 2.

In-hospital mortality in infective endocarditis patients.

Total
(n = 3,085)
IE + cancer
(n = 359)
IE – cancer
(n = 2,726)
P -value
Death 524/3,085 (17.0%) 84/359 (23.4%) 440/2,726 (16.1%) <0.001
Cause of death
Cardiovascular 149/523 (28.5%) 15/84 (17.9%) 134/439 (30.5%) 0.067
Non-cardiovascular 155/523 (29.6%) 25/84 (29.8%) 130/439 (29.6%)
Cardiovascular + Non-cardiovascular 190/523 (36.3%) 39/84 (46.4%) 151/439 (34.4%)
Unknown 29/523 (5.5%) 5/84 (6.0%) 24/439 (5.5%)
If cardiovascular:
Heart failure 239/339 (70.5%) 40/54 (74.1%) 199/285 (69.8%) 0.530
Arrhythmia 41/339 (12.1%) 3/54 (5.6%) 38/285 (13.3%) 0.108
Cardiac perforation/tamponade 11/339 (3.2%) 4/54 (7.4%) 7/285 (2.5%) 0.080
Acute MI 7/339 (2.1%) 2/54 (3.7%) 5/285 (1.8%) 0.309
Cerebral embolism 41/339 (12.1%) 4/54 (7.4%) 37/285 (13.0%) 0.249
Pulmonary embolism 13/339 (3.8%) 0/54 (0.0%) 13/285 (4.6%) 0.236
Peripheral embolism 3/339 (0.9%) 0/54 (0.0%) 3/285 (1.1%) >0.999
If non-cardiovascular:
Neoplasia 12/345 (3.5%) 11/64 (17.2%) 1/281 (0.4%) <0.001
Sepsis 265/345 (76.8%) 38/64 (59.4%) 227/281 (80.8%) <0.001

MI, Myocardial infarction.