TABLE 3.
CRCL | Same dose (mg) | Simulated trough conc. (mg/L) Mean ± S.D | Tailored dose (mg) | Simulated trough conc. (mg/L) Mean ± S.D |
---|---|---|---|---|
20 ml/min | 1,000 | 33.3 ± 7.54 a | 400 | 13.3 ± 3.01 |
60 ml/min | 1,000 | 23.9 ± 5.73 a | 600 | 14.4 ± 3.44 |
100 ml/min | 1,000 | 18.0 ± 4.56 | 800 | 14.4 ± 3.65 |
140 ml/min | 1,000 | 13.7 ± 3.79 | 1,000 | 13.7 ± 3.79 |
Above target trough concentration range (10–20 mg/l).