TABLE 2.
Left ventricular ultrasonography before and after chemotherapy ( ± s).
| T0 | T2 | T4 | T6 | T8 | |
|---|---|---|---|---|---|
| LVEF (%) | 66.65 ± 4.13 | 65.57 ± 5.25 | 62.34 ± 5.21# | 60.73 ± 5.65# | 59.43 ± 6.99# |
| GLS (%) | −22.6 ± 1.77 | −19.79 ± 2.38# | −18.17 ± 3.04# | −16.96 ± 3.65# | −15.94 ± 4.03# |
| GWI (mmHg%) | 1959.14 ± 294.34 | 1876.75 ± 309.1* | 1783.51 ± 314.37# | 1661.89 ± 321.25# | 1552.58 ± 400.26# |
| GWE (%) | 94.44 ± 1.91 | 93.08 ± 2.36# | 91.95 ± 3.12# | 89.62 ± 5.49# | 87.84 ± 6.33# |
| 3D-GLS (%) | −19.81 ± 1.69 | −18.09 ± 2.41# | −16.72 ± 2.76# | −15.82 ± 3.71# | −14.86 ± 4.03# |
| 3D-GCS (%) | −24.61 ± 3.42 | −21.73 ± 3.62# | −19.87 ± 3.84# | −18.16 ± 4.51# | −17.7 ± 4.37# |
| 3D-GAS (%) | −31.46 ± 4.73 | −29.65 ± 5.23# | −28.39 ± 4.75# | −27 ± 4.58# | −25.65 ± 4.48# |
| 3D-GRS (%) | 34.8 ± 9.06 | 33.54 ± 9.12 | 31.8 ± 7.04* | 30.14 ± 7.05# | 28.85 ± 7.14# |
LVEF, left ventricular ejection fraction; GLS, global longitudinal strain; GWI, global myocardial work index; GWE, myocardial work efficiency; 3D-GLS, left ventricular three-dimensional longitudinal peak strain; 3D-GCS, left ventricular three-dimensional peripheral peak strain; 3D-GAS, left ventricular three-dimensional area peak strain; 3D-GRS, left ventricular three-dimensional radial peak strain. #p < 0.05 compared with T0; *p < 0.01 compared with T0.