TABLE 1.

Absolute quantitation of purine metabolites in serum and liver of rats (mean ± S.E.M).

Metabolites	Levels in serum (μg/ml)		Levels in liver (mg/g)
	Control group (n = 10)	DEN group (n = 20)	Control group (n = 10)	DEN group (n = 20)
Xanthine	0.045 ± 0.014	0.031 ± 0.003*	41.68 ± 3.92	91.44 ± 4.35**
Adenine	1.41 ± 0.350	1.675 ± 0.232	91.45 ± 5.1	129.59 ± 2.22**
Guanine	0.030 ± 0.002	0.186 ± 0.042**	3.38 ± 0.68	4.36 ± 0.07*
Hypoxanthine	2.921 ± 1.22	4.537 ± 1.035*	3.80 ± 0.85	8.64 ± 1.73**
Xanthosine	0.07 ± 0.0005	0.071 ± 0.0004	29.98 ± 6.16	28.00 ± 3.25
Adenosine	3.812 ± 0.044	4.662 ± 0.158**	0.065 ± 0.03	0.010 ± 0.01
Guanosine	0.015 ± 0.001	0.016 ± 0.0009	0.100 ± 0.03	0.028 ± 0.002
Inosine	4.320 ± 0.165	4.62 ± 0.158	16.28 ± 3.57	23.22 ± 0.88*
Uridine	1.286 ± 0.080	1.369 ± 0.088	17.69 ± 3.50	12.46 ± 2.2*
Uric acid	30.03 ± 0.41	36.25 ± 0.735*	56.52 ± 13.73	103.8 ± 14.92*

Note: * represent significant differences DEN group from the Control group *p < 0.05, **p < 0.01.