TABLE 2.
MDA, SOD, and GSH activity in serum and liver of rats (mean ± S.E.M).
| Control (n = 5) | DEN (n = 14) | DEN + Febu (n = 14) | ||
|---|---|---|---|---|
| Serum | MDA (nmol/ml) | 15.37 ± 1.31 | 25.81 ± 4.13 a | 13.39 ± 1.30 b |
| SOD (U/ml) | 591.07 ± 16.78 | 562.03 ± 14.34 a | 615.97 ± 13.53 b | |
| GSH (μmol/ml) | 22.3 ± 1.13 | 13.4 ± 1.23 a | 18.2 ± 2.13 b | |
| Liver tissue | MDA (nmol/mgprot) | 2.64 ± 0.30 | 7.12 ± 0.57 a | 4.34 ± 0.59 b |
| SOD (U/mgprot) | 846.47 ± 26.06 | 724.20 ± 10.75 a | 704.53 ± 18.28 | |
| GSH (μmol/gprot) | 7.81 ± 0.45 | 4.45 ± 0.23 a | 6.74 ± 0.46 b | |
MDA, malondialdehyde; SOD, superoxide dismutase; GSH, glutathione.
a
Note: represent significant differences between the DEN group and the Control group (*p < 0.05).
b
represent significant differences between the DEN + Febu group and the DEN group (#p < 0.05).