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. 2021 Nov 11;8:702206. doi: 10.3389/fmolb.2021.702206

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Copyright © 2021 Zhang, He, Li, Xu, Chen, Liu, Hu, Xiong and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression of MXD3 in tissues (A) and WHO subtypes (D) of glioma. Differential expression of MXD3 in 1p/19q codeletion (B) and IDH mutation status (E). Differential expression of MXD3 promoter methylation in tissues (C) and WHO subtypes (F) of glioma. Representative images of MXD3 immunohistochemistry in glioma. The image shows a 16x magnification. Scale bars = 50 μm (normal (G), glioma (H). OS of MXD3 expression in primary glioma (I) and recurrent glioma (J). OS of MXD3 promoter methylation status in primary glioma (K) and recurrent glioma (L).