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. Author manuscript; available in PMC: 2021 Nov 30.
Published in final edited form as: J Med Chem. 2021 Aug 20;64(17):12506–12524. doi: 10.1021/acs.jmedchem.1c00163

Figure 9. Plasma and tissue pharmacokinetics of 5B after oral administration to non-fasted mice.

Figure 9.

A. Plasma pharmacokinetics of 5 isomeric mixture vs 5B in mice after a single oral dose of 50 mg/kg. B. Comparative neuronal tissue concentrations of 5B after a single oral dose of 50 mg/kg. Vertical axis values are the same in A and B. Data are means ± SEM, each dot represents one mouse. Calculated values are in the text.