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Design of the WT and Fast variants of the selected genes. (A, top) Shown is the nucleotide sequence of a region of gdhA, the location of which was found to be conserved within the group of homologues. In gdhA this region contains 12 slow codons, highlighted in blue (original WT codons) or red (Fast variant). (A, bottom) A plot of the TDR index values of the WT (blue) and Fast (red) variants. (B) An illustration of the two GFP-fused variants created for each gene
