Table 1.
Animal nucleus | Yeast | Plant nucleus | References | Arabidopsis chloroplasts+ |
---|---|---|---|---|
METTL3 (m6A) | Ime4 (m6A) | MTA (m6A) | [39,44,45] | MTA (MS, *) |
METTL14 (m6A) | MTB (m6A) | [46,47] | MTB (MS, *) | |
VIRMA (m6A) | Virilizer (m6A) | [47,48] | ||
WTAP (m6A) | Mum2 (m6A) | FIP37 (m6A) | [49–51] | FIP37 (MS, *) |
HAKAI (m6A) | HAKAI (m6A) | [47] | ||
ZC3H13 (m6A) | [52] | |||
NSUN2 (m5C) | NSUN2 (m5C) TRM4B (m5C) |
[53–55] | ||
TRMT6/61A (m1A) TRMT61B (m1A)# |
TRMT61A (m1A) | [56,60] | ||
METTL8 (m3C) | [57] | |||
METTL1 (m7G) | [40] | |||
The Plant Proteome Database (http://ppdb.tc.cornell.edu) | At1g78140 (*), At2g41040 (*) At4g29590 (*), Ag5g44590 (*) At5g44600 (*), At5g63100 (*) |
+The putative mRNA methyltransferases in Arabidopsis chloroplasts are indicated with confirmed or predicted subcellular localization. MS, mass spectroscopy analysis; *, predicted. #TRMT61B is a mitochondria-localized methyltransferase in humans.