Table 1.
List of mRNA methyltransferases in animals, yeast, and plants alongside their putative orthologs in Arabidopsis chloroplasts
| Animal nucleus | Yeast | Plant nucleus | References | Arabidopsis chloroplasts+ |
|---|---|---|---|---|
| METTL3 (m6A) | Ime4 (m6A) | MTA (m6A) | [39,44,45] | MTA (MS, *) |
| METTL14 (m6A) | MTB (m6A) | [46,47] | MTB (MS, *) | |
| VIRMA (m6A) | Virilizer (m6A) | [47,48] | ||
| WTAP (m6A) | Mum2 (m6A) | FIP37 (m6A) | [49–51] | FIP37 (MS, *) |
| HAKAI (m6A) | HAKAI (m6A) | [47] | ||
| ZC3H13 (m6A) | [52] | |||
| NSUN2 (m5C) | NSUN2 (m5C) TRM4B (m5C) |
[53–55] | ||
| TRMT6/61A (m1A) TRMT61B (m1A)# |
TRMT61A (m1A) | [56,60] | ||
| METTL8 (m3C) | [57] | |||
| METTL1 (m7G) | [40] | |||
| The Plant Proteome Database (http://ppdb.tc.cornell.edu) | At1g78140 (*), At2g41040 (*) At4g29590 (*), Ag5g44590 (*) At5g44600 (*), At5g63100 (*) |
+The putative mRNA methyltransferases in Arabidopsis chloroplasts are indicated with confirmed or predicted subcellular localization. MS, mass spectroscopy analysis; *, predicted. #TRMT61B is a mitochondria-localized methyltransferase in humans.