Table 2.
Univariate and multivariate COX regression analyses of body composition features of colon cancer patients.
| Disease-free survival | Overall survival | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||||
| HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | |
| Skeletal muscle | ||||||||||||
| Area (cm2) | 0.99 | 0.98–1.00 | 0.170 | 0.99 | 0.98–1.00 | 0.066 | ||||||
| SMI (cm2/m2) | 0.97 | 0.95–1.00 | 0.077 | 0.96 | 0.93–1.00 | 0.045 | 0.96 | 0.93-1.00 | 0.051 | |||
| Attenuation (HU) | 0.95 | 0.92–0.98 | 0.001 | 0.95 | 0.91–0.98 | 0.003 | 0.91 | 0.87–0.95 | <0.001 | 0.91 | 0.87-0.95 | <0.001 |
| IMAT, area (cm2) | 1.03 | 1.00–1.05 | 0.024 | 1.03 | 1.01–1.06 | 0.011 | 1.05 | 1.02–1.07 | <0.001 | 1.06 | 1.03-1.09 | <0.001 |
| Visceral adipose tissue | ||||||||||||
| VAT, area (cm2) | 1.00 | 1.00–1.00 | 0.767 | 1.00 | 1.00–1.01 | 0.567 | ||||||
| VATI (cm2/m2) | 1.00 | 0.99–1.01 | 0.928 | 1.00 | 0.99–1.01 | 0.612 | ||||||
| VAT attenuation (HU) | 1.01 | 0.98–1.03 | 0.500 | 1.01 | 0.98–1.04 | 0.383 | ||||||
| Subcutaneous adipose tissue | ||||||||||||
| SAT, area (cm2) | 1.00 | 1.00–1.00 | 0.899 | 1.00 | 1.00–1.00 | 0.938 | ||||||
| SATI (cm2/m2) | 1.00 | 0.99–1.01 | 0.856 | 1.00 | 0.99–1.01 | 0.996 | ||||||
| SAT attenuation (HU) | 1.00 | 0.99–1.01 | 0.966 | 1.00 | 0.99–1.01 | 0.868 | ||||||
The Cox model was adjusted for age (categorical), Charlson Comorbidity Index (categorical), alcohol consumption (categorical), and AJCC stage (categorical).
CI, confidence interval; HR, hazard ratio; IMAT, intramuscular adipose tissue; SAT, subcutaneous adipose tissue; SATI, subcutaneous fat index; SMI, skeletal muscle index; VAT, visceral adipose tissue; VATI, visceral fat index.
Bold was used to highlight values that were statistically significant (< 0.05).