Table 3.
Univariate and multivariate COX regression analyses of body composition features of rectal cancer patients.
| Disease-free survival | Overall survival | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||||
| HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | |
| Skeletal muscle | ||||||||||||
| Area (cm2) | 0.99 | 0.98–1.00 | 0.150 | 0.98 | 0.97–1.00 | 0.009 | 0.98 | 0.96-0.99 | 0.009 | |||
| SMI (cm2/m2) | 0.97 | 0.94–1.01 | 0.130 | 0.95 | 0.91–0.99 | 0.022 | 0.96 | 0.91-1.00 | 0.061 | |||
| Attenuation (HU) | 0.98 | 0.95–1.02 | 0.307 | 0.98 | 0.95–1.02 | 0.435 | ||||||
| IMAT, area (cm2) | 1.01 | 0.98–1.04 | 0.542 | 1.00 | 0.96–1.05 | 0.867 | ||||||
| Visceral adipose tissue | ||||||||||||
| VAT, area (cm2) | 1.00 | 0.99–1.00 | 0.439 | 1.00 | 0.99–1.00 | 0.272 | ||||||
| VATI (cm2/m2) | 1.00 | 0.99–1.01 | 0.588 | 1.00 | 0.98–1.01 | 0.501 | ||||||
| VAT attenuation (HU) | 1.03 | 1.00–1.06 | 0.047 | 1.02 | 0.99–1.05 | 0.196 | 1.04 | 1.00–1.07 | 0.030 | 1.03 | 0.99-1.06 | 0.123 |
| Subcutaneous adipose tissue | ||||||||||||
| SAT, area (cm2) | 1.00 | 0.99–1.00 | 0.350 | 1.00 | 0.99–1.00 | 0.467 | ||||||
| SATI (cm2/m2) | 1.00 | 0.99–1.00 | 0.408 | 1.00 | 0.99–1.01 | 0.717 | ||||||
| SAT attenuation (HU) | 1.02 | 1.00–1.04 | 0.077 | 1.02 | 1.00–1.04 | 0.098 | ||||||
The Cox model was adjusted for age (categorical), Charlson Comorbidity Index (categorical), alcohol consumption (categorical), and AJCC stage (categorical).
CI, confidence interval; HR, hazard ratio; IMAT, intramuscular adipose tissue; SAT, subcutaneous adipose tissue; SATI, subcutaneous fat index; SMI, skeletal muscle index; VAT, visceral adipose tissue; VATI, visceral fat index.
Bold was used to highlight values that were statistically significant (< 0.05).