TABLE 4.

Comparison of laboratory test results with paired samples of aqueous humor and serum collected at time of presentation and 2 to 53 weeks thereafter^a

Characteristic	Patient no.
	1	2	3	4	5	6	7	8	9
Time interval (wk)	6	6	2	6	6	10	22	21	53
Anti-Toxoplasma IgG level in serum/anti-Toxoplasma IgG level in aqueous humor (IU)
d	392/0	86/0	320/127	10/0	285/0	350/280	50/12	22/0	2,000/1,500
i	310/0	86/17	350/280	15/73	228/0	350/80	34/6	26/0	308/1,490
C
d	0	0	5.9	0	0	3.7	16.8	0	0.33
i	0	20.6	3.7	428	0	5.2	14.5	0	18.7
Aqueous humor IgA (index)
d	0	0	4	0	0	0	0	0	0
i	0	0	0	0	0	0	0.3	0	0
Antibody avidity (index)
d	—	—	0.4	—	—	0.45	0.8	—	0.7
i	—	0.75	0.45	0.55	—	0.15	0.55	—	0.8
DNA amplification,
d	1	0	0	0	0	0	0	1 (vitreous)	1
Confirmatory test	PCR	C	C?, IgAb	C	Not confirmed	C?	C	PCR vitreous	C, PCR, Toxoplasma-specific IgG in serumc

^aConfirmatory results are indicated in boldface type. Abbreviations and symbols: d, sample collection at the time of presentation; i, sample collection at the indicated time after presentation; —, If no specific antibodies were detected, it was not possible to determine antibody avidity in the aqueous humor. For two patients (patients 1 and 8) with clinically typical cases, the laboratory diagnosis relied solely on PCR results. 

^bIgA levels in the serum and aqueous humor were the same. In this case, C was consistently indicative but not confirmatory. This patient had suffered from acute hepatopathy 6 weeks prior to presentation for the ocular disease. T. gondii DNA was repeatedly amplified from liver biopsy specimens. 

^cThe level of anti-Toxoplasma IgG was more than threefold higher than the baseline value at 6 weeks.