. 2021 Nov 11;11:757541. doi: 10.3389/fonc.2021.757541

Table 1.

Accordant circRNAs in comparison of tumor vs. adjacent and LNM vs. NLNM.

CircRNA	Tumor vs. Adjacent				LNM vs. NLNM				Absolute mean Log₂FC
CircRNA	Log₂FC	P value	Adjusted P value	Trend	Log₂FC	P value	Adjusted P value	Trend	Absolute mean Log₂FC
hsa_circ_0008594	1.2359	0.0001	0.0005	UP	1.0963	0.0000	0.0005	UP	1.1661
hsa_circ_0004293	1.5514	0.0001	0.0044	DOWN	0.5970	0.0063	0.0226	DOWN	1.0742
hsa_circ_0003832	1.1446	0.0043	0.0302	DOWN	0.8719	0.0017	0.0086	DOWN	1.0082
hsa_circ_0055521	1.2848	0.0005	0.0098	DOWN	0.6892	0.0006	0.0040	DOWN	0.9870
hsa_circ_0039914	1.2199	0.0010	0.0143	DOWN	0.7023	0.0059	0.0216	DOWN	0.9611
hsa_circ_0007610	1.1651	0.0021	0.0201	DOWN	0.6466	0.0014	0.0074	DOWN	0.9058
hsa_circ_0039522	1.1307	0.0002	0.0063	DOWN	0.6397	0.0040	0.0161	DOWN	0.8852
hsa_circ_0010146	1.0633	0.0033	0.0264	DOWN	0.6823	0.0040	0.0161	DOWN	0.8728
hsa_circ_0052320	0.8919	0.0090	0.0452	DOWN	0.8238	0.0001	0.0010	DOWN	0.8579
hsa_circ_0008351	1.0270	0.0020	0.0199	DOWN	0.6277	0.0006	0.0040	DOWN	0.8274
hsa_circ_0000014	1.0379	0.0012	0.0150	DOWN	0.6167	0.0079	0.0268	DOWN	0.8273
hsa_circ_0008545	1.0378	0.0010	0.0143	DOWN	0.5876	0.0038	0.0154	DOWN	0.8127
hsa_circ_0006892	0.8542	0.0019	0.0195	DOWN	0.7092	0.0000	0.0004	DOWN	0.7817
hsa_circ_0008884	0.9338	0.0094	0.0461	UP	0.5864	0.0069	0.0241	UP	0.7601
hsa_circ_0000508	0.8637	0.0032	0.0261	DOWN	0.6366	0.0003	0.0024	DOWN	0.7501
hsa_circ_0001666	0.8418	0.0051	0.0330	DOWN	0.5883	0.0031	0.0133	DOWN	0.7151
hsa_circ_0047398	0.7966	0.0034	0.0269	DOWN	0.5899	0.0020	0.0095	DOWN	0.6932
hsa_circ_0083377	0.6975	0.0063	0.0369	UP	0.6214	0.0003	0.0025	UP	0.6595
hsa_circ_0000664	0.6970	0.0079	0.0423	UP	0.6134	0.0001	0.0011	UP	0.6552

Accordant circRNAs in comparison of Tumor vs. Adjacent and LNM vs. NLNM were ranked by the absolute mean value of Log₂FC. circRNA, circular RNA; LNM, lymph node metastasis; NLNM, non-lymph node metastasis; FC, fold change.