Figure 1.

BPLF1-interacting proteins involved in autophagy related pathways identified by tandem mass spectrometry. (A) List of the 19 most abundant BPLF1 interacting proteins involved in autophagy identified by mass spectrometry. The values are derived from the mean of two independent experiments. ID = protein ID, MW = molecular weight, Unique Pep = number of unique peptides mapping to the protein, PSM = number of peptide spectrums matched to the protein. (B) Network diagram illustrating the interaction of the autophagy/vesicular transport related proteins enriched in the BPLF1 interactome. The network was created using STRING with Markov clustering algorithm (MCL) where each cluster is color annotated. The annotated interactions are color coded based on their source: curated databases (cyan line), experimentally determined (pink line), gene neighborhood (dark green line), gene fusions (red line), gene co-occurrence (dark blue), text mining (light green line), co-expression (black line) and protein homology (purple line)