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. 2021 Feb 16;17(11):3577–3591. doi: 10.1080/15548627.2021.1885183

Figure 5.

Figure 5.

CD36 is involved in immunoglobulin class switching in vitro. (A) Representative contour plot showing IgA staining in CH12 and CH12 KO cells stimulated with 10 μg/mL anti-CD40, 8 ng/mL IL4, and 8 ng/mL TGFB for 3 d. (B) Percentage of IgA+ cells among CH12 and CH12 KO cells after the stimulation. (C) Quantitative (RT)-PCR analysis of transcripts encoding Aicda in CH12 and CH12 KO cells after stimulation. Data are representative of three independent experiments. *P < 0.05, **P < 0.01 and ***P < 0.001 (Mann-Whitney test)