. 2021 Nov 28;13(1):1997560. doi: 10.1080/19490976.2021.1997560

Table 3.

Infant head circumference growth-associated fecal microbial taxa that significantly moderated vaginal delivery effects

Fecal microbial taxon	Coefficient	95% confidence intervals	p value	McFadden’s R²
Acutalibacteraceae	1.66	[1.65, 1.67]	<2x10⁻¹⁶	0.03
Bacteroidaceae	0.21	[0.20, 0.22]	<2x10⁻¹⁶	0.02
Bacteroides_B	1.37	[1.35, 1.38]	<2x10⁻¹⁶	0.03
dorei	0.10	[0.09, 0.11]	<2x10⁻¹⁶	0.02
vulgatus	1.11	[1.10, 1.12]	<2x10⁻¹⁶	0.02
Dialisteraceae	ns
Dialister	ns
invisus	1.06	[1.05, 1.07]	<2x10⁻¹⁶	0.02
Erysipelatoclostridiaceae	ns
Coprobacillus	−1.32	[−1.33, −1.31]	<2x10⁻¹⁶	0.02
Erysipelatoclostridium	1.50	[1.49, 1.51]	<2x10⁻¹⁶	0.03
Lachnospiraceae	1.47	[1.44, 1.49]	<2x10⁻¹⁶	0.03
Eubacterium_E	1.10	[1.09, 1.11]	<2x10⁻¹⁶	0.02
Hungatella	ns
effluvii	0.88	[0.86, 0.89]	<2x10⁻¹⁶	0.03
Megasphaeraceae	ns
Megasphaera	0.97	[0.96, 0.98]	<2x10⁻¹⁶	0.03
Mycobacteriaceae	0.82	[0.81, 0.82]	<2x10⁻¹⁶	0.02
Rikenellaceae	ns
Alistipes	ns
putredinis	0.21	[0.20, 0.22]	<2x10⁻¹⁶	0.02
Ruminococcaceae	ns
Faecalibacterium	1.54	[1.54, 1.55]	<2x10⁻¹⁶	0.03
prausnitzii	3.70	[3.69, 3.72]	<2x10⁻¹⁶	0.03

Legend: Significance of moderation was evaluated by the Wald statistic (p< 0.05; FP<1%), model coefficients with 95% confidence intervals and McFadden’s R² on cumulative link mixed regression of infant head circumference growth trajectories for the interaction of delivery mode and abundance of a given fecal microbial taxon, with postmenstrual age, and delivery mode and the given fecal microbial taxon abundance individually as fixed effects, plus patient as a random effect. Head circumference growth groups are defined in legend for Figure 1. Abbreviations: ns = nonsignificant.