Figure 2.

Analysis of solution binding of c2C7, m4A2, m9B6 and cG250 to monomeric hCAIX by ITC. Binding isotherm curves are shown for the interaction of these antibodies to monomeric hCAIX. In all experiments the antibodies were titrated into a cell containing monomeric hCAIX. Concentrations of mAbs in the syringe were 37.5 µM and the concentration of the monomeric hCAIX in the cell was 10 µM