TABLE 2.
Secondary hemostatic factors.
| Men [mean ± SD median (IQR)] | Women [mean ± SD median (IQR)] | Sex difference | Study | |
|
FVII:C (%)
FVII:ag (%) |
3m: 104 ± 30 3m: 99 ± 31 |
3m: 116 ± 30 3m: 114 ± 34 |
p = 0.04 p = 0.01 |
Kain et al., 2001 |
| FXIIa (ng/mL) | 3m: 2.2 ± 1.0 | 3m: 2.4 ± 1.1 | NS | Kain et al., 2001 |
| FXI (UI/mL) | 1m: 1.13 ± 0.32 (0.14 higher in women than in men) | 95%CI: 0.09–0.19 | Santamaria et al., 2007 | |
| AT III (% activity) | <2d: 102.5 ± 12.4 1w: 106.1 ± 13.8 1m: 113.5 ± 15.7 3m: 113.3 ± 12.5 |
<2d: 103.6 ± 16.9 1w: 114.4 ± 16.6 1m: 112.8 ± 12.5 3m: 112.6 ± 13.2 |
NS | Haapaniemi et al., 2002 |
| β-antithrombin (% activity) | <2d: 105.9 ± 17.4 | NS | de la Morena-Barrio et al., 2015 | |
| Thrombin-antithrombin (mg/L) | <2d: 7.9 ± 9.1 1w: 6.6 ± 8.6 1m: 4.5 ± 3.3 3m: 6.0 ± 6.2 |
NS | Haapaniemi et al., 2004 | |
| protein S (% antigen) | <2d: 104.7 ± 19.8 1w: 87.8 ± 4.3 1m: 85.5 ± 28.5 3m: 91.2 ± 31.1 |
<2d: 86.2 ± 23.0 1w: 72.3 ± 34.2 1m: 80.6 ± 32.8 3m: 73.5 ± 28.0 |
p < 0.05 NS NS p < 0.01 |
Haapaniemi et al., 2002 |
| Protein C (% activity) | <2d: 118.6 ± 28.4 1w: 108.3 ± 42.4 1m: 109.0 ± 35.7 3m: 109.0 ± 43.5 |
<2d: 116.0 ± 30.6 1w: 125.8 ± 44.1 1m: 119.8 ± 44.7 3m: 111.7 ± 40.6 |
NS | Haapaniemi et al., 2002 |
| Fibrinogen (g/L) | <10d: 4.57 (4.37–4.78) 3m: 3.86 (3.63–4.12) |
<10d: 4.40 (4.22–4.58) 3m: 3.82 (3.64–4.02) |
↑ in women with TACI (p = 0.021) |
Carter et al., 1997 |
| Fibrinogen (g/L) | 3m: 3.8 ± 1.3 | 3m: 3.7 ± 1.3 | NS | Kain et al., 2001 |
| Fibrinogen (g/L) | 3h: 3.4 ± 0.8 6h: 3.1 ± 0.8 24h: 3.4 ± 0.8 |
NS | Skoloudik et al., 2010 | |
| Fibrinogen (g/L) | <24h: 3.9 ± 1.2 | <24h: 4.0 ± 1.8 | NS | Kisialiou et al., 2012 |