TABLE 3.

Fibrinolysis factors.

	Men [mean ± SD median (IQR)]	Women [mean ± SD median (IQR)]	Sex difference	Study
D-dimer (μg/mL)	<2d: 0.66 ± 0.56 1w: 1.61 ± 3.18 1m: 0.79 ± 0.89 3m: 0.49 ± 0.42		NS	Haapaniemi et al., 2004
D-dimer (μg/mL)	3h: 0.31 ± 0.40 6h: 0.86 ± 1.04 24h: 0.59 ± 1.00		NS	Skoloudik et al., 2010
D-dimer (μg/mL)	0.95 ± 0.24*	1.25 ± 0.31*	p < 0.001	Li et al., 2018
PAI-1 (U/mL)	3m: 11.4 (10.2–12.7)	3m: 15.7 (13.7–18.1)	p = 0.001	Mansfield et al., 1998
PAI-1 activity U/mL) PAI-1:ag (U/mL)	3m: 16.1 ± 11.7 3m: 13.3 ± 11.0	3m: 19.3 ± 10.8 3m: 18.2 ± 13.5	p = 0.04 p = 0.04	Kain et al., 2001
PAI-1 activity (U/mL) PAI-1:ag (U/mL)	3m: 14.1 ± 2.0 3m: 11.1 ± 2.4	3m: 19.2 ± 1.7 3m: 16.2 ± 2.1	p < 0.05 p < 0.05	Kain et al., 2002
PAI-1 (AU/mL)	<2d: 17.2 ± 7.8 1w:11.2 ± 9.2 1m: 14.4 ± 7.9 3m: 15.8 ± 8.4		NS	Haapaniemi et al., 2004
PAI-1 (ng/mL)	96.7 ± 38.9*	125.4 ± 49.4*	p < 0.05**	Saidi et al., 2007
t-PA:ag (ng/mL)	<2w: 9.4 (6.7–12.1) 6m: 10.3 (9.1–14.6)	<2d: 10.1 (7.4–12.6) 6m: 10.9 (7.3–15.3)	NS	Jeppesen et al., 1998
t-PA:ag (ng/mL)	3m: 11.5 (10.7–12.2)	3m: 11.7 (10.8–12.6)	NS	Mansfield et al., 1998
t PA:ag (ng/mL)	3m: 11.4 ± 1.6	2m: 12.0 ± 1.7	NS	Kain et al., 2001
t-PA:ag (ng/mL)	0.8 ± 0.4*	0.7 ± 0.3*	NS	Saidi et al., 2007
t-PA:ag (ng/mL)	<2d: 8.8 ± 4.2 1w: 8.4 ± 3.4 1m: 8.3 ± 3.2 3m: 8.7 ± 4.3		NS	Haapaniemi et al., 2004
F1.2 (ng/mL)	3–6m: 0.9 (0.3–2.4)	3–6m: 1.0 (0.4–2.8)	p = 0.02	Furie et al., 2004
F1.2 (nmol/L)	<2d: 1.7 ± 0.9 1w: 1.7 ± 1.1 1m: 1.4 ± 0.8 3m: 1.6 ± 1.4		NS	Haapaniemi et al., 2004

* Unknown in which phase blood was drawn.

**Increased in women with ischemic stroke compared to controls, no difference in men between ischemic stroke patients and controls.