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. 2021 Nov 23;2021:3928323. doi: 10.1155/2021/3928323

(c) Cytochrome P450 CYP lipid peroxidation antioxidant (anti-inflammatory) enzymes

GEO ID GSE35961 GSE63027 GSE63027 GSE53381
Comparison MCD+HFD vs. NCD MAT1A-KO vs. WT GNMT-KO vs. WT HFCD vs. NCD
Gene symbol
 CYP11A1 -2.023
 CYP11B2 -3.851 -1.459
 CYP17A1 -2.781 7.210
 CYP1B1 3.080 1.496
 CYP20A1 2.293
 CYP21A2
 CYP2B10 -3.160 12.086
 CYP2B13 9.455 3.648 7.655
 CYP2B9 48.303 6.811 4.811
 CYP2C29 -4.350 -2.577 -1.736 1.663
 CYP2C37 -2.233 -3.070 -2.395 1.834
 CYP2C38 -1.531 -2.784 2.694 2.499
 CYP2C39 2.771 1.751
 CYP2C40 1.830
 CYP2C54 -113.732 -1.679 -3.681 1.907
 CYP2C55 1.681 -2.085 4.526
 CYP2C65 1.413
 CYP2F1
 CYP2J11 1.347 1.621
 CYP2J2
 CYP2J5 -4.063 -1.569 1.442
 CYP2R1 -2.226 -2.032 1.441
 CYP2S1 -1.756
 CYP2U1 -6.007 -1.990 1.473
 CYP2W1
 CYP3A7
 CYP4A10 2.235
 CYP4A11
 CYP4A12A -7.436 3.664 1.670 2.931
 CYP4A12B 2.789
 CYP4A14 3.575 -13.392 16.111 14.158
 CYP4A31 -2.773 13.473
 CYP4B1 -1.598 -1.619
 CYP4F13 -2.811 1.525
 CYP4F18
% up 6/44 (13.6%) 4/44 (9.1%) 5/44 (11.4%) 22/44 (50%)
% down 13/44 (29.5%) 8/44 (18.2%) 8/44 (18.2%) 1/44 (2.3%)