Table 2.
Study characteristics and populations included in the eligible studies.
| Author (reference) | Study year | Study area | Study design | Study populations | Sample size | Sex | Age, yrs. | |
|---|---|---|---|---|---|---|---|---|
| M | F | |||||||
| Muhie [24] | 2019 | Gondar | CS | Hospitalized adult patients with ascites. | 24 | NR | NR | NR |
| Adhanom and Desalegn [25] | 2017 | Addis Ababa | CS | Patients diagnosed with CLD, cirrhosis, HCC, hepatitis as labeled on the medical chart. | 117 | 107 | 10 | Median: 45 |
| Ayele and Gebre-Selassie [26] | 2013 | Addis Ababa | CS | CLD diagnosed patients based on history, clinical, ultrasound, and impaired liver function tests. | 120 | 76 | 44 | Mean: 40.99 ± 14.00 |
| Gaddisa Desu [27] | 2019 | Jimma | CS | Adult clinically diagnosed CLD patients admitted at medical ward and on follow-up at GI clinic with. | 96 | 66 | 30 | 20 to 49 : 76, ≥50 : 16, 15–19 : 4 |
| Taye et al. [28] | 2014 | Bale robe | CS | All patients with chronic hepatitis. | 578 | 322 | 256 | Mean age: 34 |
| Tsega et al. [29] | 1995 | Addis Ababa | CC | The only biopsy-proven cases of patients with chronic hepatitis (14), cirrhosis (156), and HCC (68). | 238 | 170 | 68 | Mean: 42 ± 13.3 |
| Mohammed and Ali [30] | 2014 | Addis Ababa (multicenter) | CS | Clinically diagnosed CLD patients. | 117 | 82 | 55 | Median = 39 (18 to 78) |
| Abdelmenan et al. [31] | 2018 | Addis Ababa | CC | CLD patients were diagnosed based on clinical features, laboratory tests, imaging techniques, and when available histological tissues assessment. | 812 | 470 | 342 | Mean: 40.7 ± 15.4 |
| Orlien et al. [32] | 2018 | Harar | CS | Adult patients presenting for the first time with features of CLD based on the presence of suggestive clinical and ultrasound features. | 150 | 108 | 42 | Median: 30 |
| Orlien et al.∗ [33] | 2018 | Harar | CC | Adult patients presenting for the first time with features of CLD based on the presence of suggestive clinical and ultrasound features. | 150 | 108 | 42 | Median (IQR): 30 (25–40) |
| Terefe Tesfaye et al. [34] | 2019 | Multicentera | CS | Hospitalized adult CLD patients diagnosed based on suggestive clinical and/or ultrasound findings. | 119 | 85 | 24 | Median (IQR): 38(30–40) |
| Bihonegn and Ayalewu [35] | 2019 | Mekelle | CC | CLD (cases) and non-CLD (controls) patients who were attending in the GI unit. | 94 | 77 | 17 | Mean: 41 ± 13 |
aMulticenter: Jimma, Addis Ababa, and Harar, CC: case-control, CS: cross-sectional, IQR: interquartile range, CLD: chronic liver disease, HCC: hepatocellular carcinoma.