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. 2021 Nov 11;12:759172. doi: 10.3389/fphar.2021.759172

FIGURE 3.

FIGURE 3

HT inhibits accumulation of MDSCs in the mice with orthotopic pancreatic tumor. The tumors, spleens and BM of mice in the control group and the HT treatment group were isolated. The proportion of CD11b + Gr-1+ cells in the tumors (n = 5 in each group) (A,B), spleens (n = 5 in each group) (C,D) and BM (n = 3 in each group) (E,F) was detected using flow cytometry. Gr-1 expression in mouse pancreatic tumors was detected using IHC. Representative images and quantification of Gr-1 from the control group and the HT treatment group (G,H). Eight images from four mice in each group were analyzed for average pixel intensity and statistics (*p < 0.05, **p < 0.01, ****p < 0.0001).