TABLE 2.
Comparison of clinical symptom scores.
| Drug group (n = 181) | Control group (n = 186) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline a | 3 months later | P-value | D-value b | Baseline | 3 months later | P-value | D-value b | P-value c | |
| Cough | 6.18 ± 2.00 | 3.03 ± 1.64 d | <0.001 | 3.15 ± 1.88 | 6.06 ± 1.84 | 3.76 ± 1.70 | <0.001 | 2.31 ± 1.70 | <0.001 |
| Expectoration | 7.36 ± 2.35 | 4.57 ± 2.89 d | <0.001 | 2.78 ± 2.53 | 7.21 ± 2.28 | 6.05 ± 2.85 | <0.001 | 1.16 ± 2.23 | <0.001 |
| Expectoration volume | 5.20 ± 2.40 | 2.62 ± 2.17 d | <0.001 | 2.59 ± 2.04 | 5.44 ± 2.46 | 3.10 ± 2.18 | <0.001 | 2.33 ± 1.95 | 0.251 |
| Total cough score | 18.75 ± 5.67 | 10.23 ± 5.77 d | <0.001 | 8.52 ± 4.71 | 18.71 ± 5.35 | 12.90 ± 5.44 | <0.001 | 5.81 ± 4.09 | <0.001 |
| Dyspnea | 2.32 ± 2.34 | 1.03 ± 1.56 | <0.001 | 1.29 ± 2.08 | 2.19 ± 2.19 | 1.26 ± 1.70 | <0.001 | 0.94 ± 1.71 | 0.180 |
| Hemoptysis | 1.11 ± 2.00 | 0.36 ± 1.17 | <0.001 | 0.75 ± 2.10 | 1.39 ± 1.98 | 0.47 ± 1.22 | <0.001 | 0.92 ± 1.87 | 0.191 |
| Chest pain | 0.60 ± 1.43 | 0.23 ± 0.92 | 0.003 | 0.36 ± 1.17 | 0.77 ± 1.52 | 0.26 ± 0.95 | <0.001 | 0.52 ± 1.47 | 0.131 |
| Total symptom score | 22.77 ± 7.06 | 11.85 ± 7.05 d | <0.001 | 10.92 ± 5.89 | 23.06 ± 6.11 | 14.89 ± 6.35 | <0.001 | 8.18 ± 4.77 | <0.001 |
Data are presented as mean ± SD except as otherwise noted.
There were no statistical differences in all the clinical symptom scores between the two groups during exacerbation (p > 0.05).
D-value, difference value, the difference between baseline and 3 months later.
The p-value of the d-value between two groups.
There were statistical differences between the two groups 3 months later (p < 0.05).